Pathophysiological affair between protein kinase D and epithelial ovarian cancer: A roadmap towards translating the mechanism from bench to bedside.

Adhiraj Roy

Biochimica et biophysica acta. Reviews on cancer, 2026

Protein Kinase D2 Promotes Neuroendocrine Phenotypes of Prostate Cancer by Regulating Aurora A Kinase and N-myc Complex (Abstract ID: 171750)

Wenxiao Zheng, Adhiraj Roy, Q. Wang

Journal of Pharmacology and Experimental Therapeutics, 2025

Advances in the molecular level understanding of G-protein coupled receptor.

Adhiraj Roy

Progress in Molecular Biology and Translational Science, 2023

A mononuclear N,N,N,O donor schiff base Cu(II) complex inhibits bacterial biofilm formation and promotes apoptosis and cell cycle arrest in prostate cancer cells.

Samik Biswas, Abdul Wasai, Mrinmoy Ghosh, C. Rizzoli, Adhiraj Roy, S. Saha, Supratim Mandal

Journal of Inorganic Biochemistry, 2023

Pharmacological inhibition of protein kinase D suppresses epithelial ovarian cancer via MAPK/ERK1/2/Runx2 signalling axis.

Komal Tyagi, Adhiraj Roy, Supratim Mandal

Cellular Signalling, 2023

Protein kinase D2 and 3 promote prostate cancer cell bone metastasis by positively regulating Runx2 in a MEK/ERK1/2-dependent manner.

Adhiraj Roy, S. Prasad, Yuzhou Chen, Ya-Ling Chao, Yu Liu, Jinjun Zhao, Q. Wang

American Journal of Pathology, 2023

Runt-related transcription factors in human carcinogenesis: a friend or foe?

Adhiraj Roy, Shivi Chauhan, S. Bhattacharya, Vibhuti Jakhmola, Komal Tyagi, Abha Sachdeva, Abdul Wasai, Supratim Mandal

Journal of Cancer Research and Clinical Oncology, 2023

Human microbial dysbiosis as driver of gynecological malignancies.

Supratim Mandal, S. Bandyopadhyay, Komal Tyagi, Adhiraj Roy

Biochimie, 2022

Protein kinase D promotes prostate cancer cell bone metastasis by positively regulating Runx2 in a MEK/ERK1/2-dependent manner

Adhiraj Roy, S. Prasad, Ya-Ling Chao, Jinjun Zhao, Q. Wang

bioRxiv, 2022

Loss of Protein Kinase D2 Activity Protects Against Bleomycin-induced Dermal Fibrosis in Mice

Li-ping Chen, Jinjun Zhao, Ya-Ling Chao, Adhiraj Roy, Wen-dong Guo, Jiabi Qian, Wanfu Xu, Z. Xing, Xiaoju Lai, B. Lu, F. Deng, Q. J. Wang

bioRxiv, 2021

Recent advancements in therapeutic targeting of the Warburg effect in refractory ovarian cancer: A promise towards disease remission.

Komal Tyagi, Supratim Mandal, Adhiraj Roy

Biochimica et biophysica acta. Reviews on cancer, 2021

Recent advances in understanding the molecular role of phosphoinositide-specific phospholipase C gamma 1 as an emerging onco-driver and novel therapeutic target in human carcinogenesis.

Supratim Mandal, S. Bandyopadhyay, Komal Tyagi, Adhiraj Roy

Biochimica et biophysica acta. Reviews on cancer, 2021

Targeting Tumor Microenvironment Through Nanotheranostics

B. Deswal, S. Kapoor, Adhiraj Roy

Nanomedicine for Cancer Diagnosis and Therapy, 2021

Evaluating the current status of protein kinase C (PKC)-protein kinase D (PKD) Signalling Axis as a novel therapeutic target in ovarian Cancer.

Komal Tyagi, Adhiraj Roy

Biochimica et biophysica acta. Reviews on cancer, 2020

Oncogenic potential of nucleoporins in non-hematological cancers: recent update beyond chromosome translocation and gene fusion

Adhiraj Roy, G. Narayan

Journal of Cancer Research and Clinical Oncology, 2019

Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway

J. Ye, Sabyasachi Das, Adhiraj Roy, Wenzhong Wei, Huachen Huang, Joshua M. Lorenz-Guertin, Qian Xu, Tija C. Jacob, Bing Wang, Dandan Sun, Q. Wang

Molecular Neurobiology, 2018

Protein Kinase D2 Modulates Cell Cycle by Stabilizing Aurora A Kinase at Centrosomes

Adhiraj Roy, M. Veroli, S. Prasad, Q. Wang

Molecular Cancer Research, 2018

Protein Kinase D: A Potential Therapeutic Target in Prostate Cancer

Adhiraj Roy, Q. J. Wang

Molecular and Cellular Pharmacology, 2017

Protein Kinase D Signaling in Cancer: A Friend or Foe?

Adhiraj Roy, J. Ye, F. Deng, Q. Wang

Biochimica et biophysica acta. Reviews on cancer, 2017

Methylglyoxal Inhibits Expression of the Glucose Transporter Genes by Inactivating Rgt2/Snf3 Glucose Sensors

S. Hashmi, Adhiraj Roy

2016

The glucose metabolite methylglyoxal inhibits expression of the glucose transporter genes by inactivating the cell surface glucose sensors Rgt2 and Snf3 in yeast

Adhiraj Roy, S. Hashmi, Zerui Li, Angela D. Dement, Kyu Hong Cho, Jeong‐Ho Kim

Molecular Biology of the Cell, 2016

Assessing Glucose Uptake through the Yeast Hexose Transporter 1 (Hxt1)

Adhiraj Roy, Angela D. Dement, K. Cho, Jeong‐Ho Kim

PLoS ONE, 2015

Mth1 regulates the interaction between the Rgt1 repressor and the Ssn6‐Tup1 corepressor complex by modulating PKA‐dependent phosphorylation of Rgt1

Adhiraj Roy, J. Kim

2015

The Role of the Pleckstrin Homology Domain-containing Protein CKIP-1 in Activation of p21-activated Kinase 1 (PAK1)*

Yong-Bae Kim, Y. Shin, Adhiraj Roy, Jeong‐Ho Kim

Journal of Biological Chemistry, 2015

Glucose starvation-induced turnover of the yeast glucose transporter Hxt1

Adhiraj Roy, Yong-Bae Kim, K. Cho, Jeong‐Ho Kim

Biochimica et Biophysica Acta, 2014

The Glucose Signal Transduction Pathway Mediated by the Rgt2 and Snf3 Glucose Sensors in the Budding Yeast Saccharomyces cerevisiae

Adhiraj Roy

2014

Understanding the mechanism of glucose-induced relief of Rgt1-mediated repression in yeast

Adhiraj Roy, David J. Jouandot, K. Cho, Jeong‐Ho Kim

FEBS Open Bio, 2014

Construction of yeast strains useful for screening drugs that inhibit glucose uptake and glycolysis

Adhiraj Roy, Y. Shin, Jeong‐Ho Kim

Analytical Biochemistry, 2013

Evidence for a Novel Mechanism of the PAK1 Interaction with the Rho-GTPases Cdc42 and Rac

Y. Shin, Eun Hye Kim, Adhiraj Roy, Jeong‐Ho Kim

PLoS ONE, 2013

Functional dissection of the glucose signaling pathways that regulate the yeast glucose transporter gene (HXT) repressor Rgt1

David J. Jouandot, Adhiraj Roy, Jeong‐Ho Kim

Journal of Cellular Biochemistry, 2011